FADD antibody (AA 20-150)
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- Target See all FADD Antibodies
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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Binding Specificity
- AA 20-150
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This FADD antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- FADD Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human FADD (AA: 20-150) expressed in E. Coli.
- Clone
- 5A6A2
- Isotype
- IgG1
- Top Product
- Discover our top product FADD Primary Antibody
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anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 12-206) antibody
FADD Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 7-178) antibodyFADD Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 109-208) antibodyFADD Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3C3 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibodyFADD Reactivity: Mouse WB, IHC Host: Rabbit Monoclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-80) antibodyFADD Reactivity: Human, Mouse, Rat, Monkey, Pig WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (pSer191) antibodyFADD Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (N-Term) antibodyFADD Reactivity: Human WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (pSer194) antibodyFADD Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
- Alternative Name
- FADD (FADD Products)
- Background
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The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]
- Molecular Weight
- 23.3 kDa
- Gene ID
- 8772
- UniProt
- Q13158
- Pathways
- Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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