PRAS40 antibody (AA 92-276)

Catalog No. ABIN7193463

This anti-PRAS40 antibody is a Mouse Monoclonal antibody detecting PRAS40 in ELISA and FACS. Suitable for Human.

Quick Overview for PRAS40 antibody (AA 92-276) (ABIN7193463)

Target: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PRAS40 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 4A11G7

Product Details anti-PRAS40 Antibody

Binding Specificity: AA 92-276

Purpose: AKT1S1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human AKT1S1 (AA: 92-276) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for PRAS40

Target: PRAS40 (AKT1S1) (AKT1 Substrate 1 (Proline-Rich) (AKT1S1))

Alternative Name: AKT1S1

Background:

AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008]

Molecular Weight: 27.4 kDa

Gene ID: 84335

UniProt: Q96B36

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Autophagy, BCR Signaling, Warburg Effect