SAA1 antibody (AA 19-122)

Catalog No. ABIN7193595

This anti-SAA1 antibody is a Mouse Monoclonal antibody detecting SAA1 in ELISA, IHC and FACS. Suitable for Human.

Quick Overview for SAA1 antibody (AA 19-122) (ABIN7193595)

Target: SAA1 (Serum Amyloid A1 (SAA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SAA1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 1A12E5

Product Details anti-SAA1 Antibody

Binding Specificity: AA 19-122

Purpose: SAA1 Antibody

Sequence: SFFSFLGEAF DGARDMWRAY SDMREANYIG SDKYFHARGN YDAAKRGPGG AWAAEVITDA RENIQRFFGH GAEDSLADQA ANEWGRSGKD PNHFRPAGLP EKY

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human SAA1 (AA: 19-122) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200-1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for SAA1

Target: SAA1 (Serum Amyloid A1 (SAA1))

Alternative Name: SAA1

Background:

This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. [provided by RefSeq, Feb 2016]

Molecular Weight: 13.5 kDa

Gene ID: 6288

UniProt: P0DJI8

Pathways: Toll-Like Receptors Cascades