SAA1 antibody (AA 1-100)

Catalog No. ABIN7270255

This Rabbit Polyclonal antibody specifically detects SAA1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for SAA1 antibody (AA 1-100) (ABIN7270255)

Target: SAA1 (Serum Amyloid A1 (SAA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SAA1 Antibody

Binding Specificity: AA 1-100

Purpose: SAA1 Rabbit pAb

Sequence: MKLLTGLVFC SLVLGVSSRS FFSFLGEAFD GARDMWRAYS DMREANYIGS DKYFHARGNY DAAKRGPGGA WAAEVISDAR ENIQRFFGHG AEDSLADQAA

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SAA1 (NP_000322.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SAA1

Target: SAA1 (Serum Amyloid A1 (SAA1))

Alternative Name: SAA1

Background: This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.,SAA1,PIG4,SAA,SAA2,TP53I4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Lipids,Lipoproteins/Apolipoproteins,SAA1

Molecular Weight: 13kDa

Gene ID: 6288

UniProt: P0DJI8

Pathways: Toll-Like Receptors Cascades