Recombinant SAA1 antibody

Catalog No. ABIN7581776

This Mouse Monoclonal antibody specifically detects SAA1 in ELISA. It exhibits reactivity toward Human.

Quick Overview for Recombinant SAA1 antibody (ABIN7581776)

Target: SAA1 (Serum Amyloid A1 (SAA1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SAA1 antibody is un-conjugated

Application: ELISA

Grade: Animal-Free

Clone: AB492-2-C08

Product Details anti-SAA1 Antibody

Expression System: Phage display

Purpose: Mouse anti- human Serum Amyloid A1

Specificity: This is an antibody developed by antibody phage display technology using a human naive antibody gene library and human serum amyloid A1 antigen. For this antibody both the heavy and light chains are cloned and expressed, generating full-length antibodies.

Characteristics: This antibody can be detected with anti-mouse Fc secondary antibodies.

Purification: Protein A purification

Immunogen: No immunization, animal-free antibody development. Antigen: human serum amyloid A1

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1-12 μg/mL as coating antibody 0.5-5 μg/mL as detection antibody Optimal working dilution should be determined by the investigator

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4,

Storage: -20 °C

Target Details for SAA1

Target: SAA1 (Serum Amyloid A1 (SAA1))

Alternative Name: Serum Amyloid A1

Background: Serum Amyloid A1 (SAA1) is a prominent acute-phase protein in humans, primarily produced by the liver in response to inflammation. It plays a role in the immune system, potentially aiding in tissue repair, acting as an antibacterial agent, and signaling the migration of immune cells to sites of infection. Levels of SAA1 can increase dramatically (up to 1000-fold) during inflammatory states triggered by infections, injury, or chronic diseases.

Molecular Weight: 12 kDa

Gene ID: 6822

NCBI Accession: NG_012021

UniProt: P02647

Pathways: Toll-Like Receptors Cascades