ADAM10 antibody

Catalog No. ABIN7193611

This Mouse Monoclonal antibody specifically detects ADAM10 in ELISA, IHC and FACS. It exhibits reactivity toward Human.

Quick Overview for ADAM10 antibody (ABIN7193611)

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADAM10 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 6C3C7

Product Details anti-ADAM10 Antibody

Purpose: ADAM10 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ADAM10 (AA: EXTRA(20-119)) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200-1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for ADAM10

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Alternative Name: ADAM10

Background:

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.

Molecular Weight: 84 kDa

UniProt: O14672

Pathways: Notch Signaling, EGFR Signaling Pathway