CX3CR1 antibody

Catalog No. ABIN7193758

Product Details anti-CX3CR1 Antibody

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CX3CR1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: CX3CR1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CX3CR1 (AA: mix) expressed in E. Coli.

Clone: 2H4C9

Isotype: IgG2a

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Alternative Name: CX3CR1 (CX3CR1 Products)

Background:

Description:

Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.

Aliases: V28, CCRL1, GPR13, CMKDR1, GPRV28, CMKBRL1

Molecular Weight: 40.4kDa

Gene ID: 1524

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin