NCR3 antibody (AA 19-135)

Catalog No. ABIN7193777

The Mouse Monoclonal anti-NCR3 antibody has been validated for ELISA, WB, IHC and FACS. It is suitable to detect NCR3 in samples from Human, Rat and Mouse.

Quick Overview for NCR3 antibody (AA 19-135) (ABIN7193777)

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This NCR3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 2D3B1

Product Details anti-NCR3 Antibody

Binding Specificity: AA 19-135

Purpose: CD337 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD337 (AA: 19-135) expressed in HEK293-6e cells supernatant.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Alternative Name: CD337

Background:

The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 21.5 kDa

Gene ID: 259197

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process