TLR1 antibody (AA 172-425)

Catalog No. ABIN7193807

The Mouse Monoclonal anti-TLR1 antibody has been validated for IHC, ELISA, FACS and ICC. It is suitable to detect TLR1 in samples from Human.

Quick Overview for TLR1 antibody (AA 172-425) (ABIN7193807)

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 3B1D8

Product Details anti-TLR1 Antibody

Binding Specificity: AA 172-425

Purpose: CD281 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD281 (AA: 172-425) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/100 - 1/500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for TLR1

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Alternative Name: CD281

Background:

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

Molecular Weight: 90.2 kDa

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades