IL-10RA antibody (AA 22-235)
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- Target See all IL-10RA (IL10RA) Antibodies
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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Binding Specificity
- AA 22-235
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IL-10RA antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CD210 (AA: extra 22-235)) expressed in E. coli.
- Clone
- 8A2A5
- Isotype
- IgG1
- Top Product
- Discover our top product IL10RA Primary Antibody
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- Application Notes
- WB:1:500 - 1:2000, ICC:1:25 - 1:200, FCM:1:200 - 1:400, ELISA:1:10000,
- Restrictions
- For Research Use only
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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- Target
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
- Alternative Name
- CD210 (IL10RA Products)
- Synonyms
- IL10R1 antibody, IL10RA antibody, CD210 antibody, CD210a antibody, CDW210A antibody, HIL-10R antibody, IL-10R1 antibody, IL10R antibody, AW553859 antibody, CDw210 antibody, CDw210a antibody, Il10r antibody, mIL-10R antibody, interleukin 10 receptor subunit alpha antibody, interleukin 10 receptor, alpha antibody, IL10RA antibody, Il10ra antibody
- Background
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Description: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Aliases: IL10RA, IL10R, CD210a, CDW210A, HIL-10R, IL-10R1
- Molecular Weight
- 63 kDa
- Gene ID
- 3587
- Pathways
- Growth Factor Binding
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