VCP antibody (AA 707-806)

Catalog No. ABIN7193883

This anti-VCP antibody is a Mouse Monoclonal antibody detecting VCP in WB, ELISA, FACS and ICC. Suitable for Human and Mouse.

Quick Overview for VCP antibody (AA 707-806) (ABIN7193883)

Target: VCP (Valosin Containing Protein (VCP))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This VCP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 8E4A4

Product Details anti-VCP Antibody

Binding Specificity: AA 707-806

Purpose: VCP Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human VCP (AA:707-806) expressed in Mammalian system

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for VCP

Target: VCP (Valosin Containing Protein (VCP))

Alternative Name: VCP

Background:

This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients.

Molecular Weight: 89.3 kDa

Gene ID: 7415

UniProt: P55072

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway