IL1A antibody

Catalog No. ABIN7193974

Product Details anti-IL1A Antibody

Target: IL1A (Interleukin 1 alpha (IL1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL1A antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: IL1A Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human IL1A (AA: extra(155-354)) expressed in E. Coli.

Clone: 6G4A5

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for IL1A

Target: IL1A (Interleukin 1 alpha (IL1A))

Alternative Name: IL1A (IL1A Products)

Background:

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

Molecular Weight: 30.6 kDa

Gene ID: 3552

Pathways: NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints