EPAS1 antibody (AA 680-870)

Catalog No. ABIN7193981

The Mouse Monoclonal anti-EPAS1 antibody has been validated for IHC, ELISA, ICC and FACS. It is suitable to detect EPAS1 in samples from Human.

Quick Overview for EPAS1 antibody (AA 680-870) (ABIN7193981)

Target: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPAS1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 1H3E12

Product Details anti-EPAS1 Antibody

Binding Specificity: AA 680-870

Purpose: HIF2a Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human HIF2a (AA: 680-870) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for EPAS1

Target: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Alternative Name: HIF2a

Background:

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]

Molecular Weight: 96.5 kDa

UniProt: Q99814

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect