CD1a antibody (APC)

Catalog No. ABIN7200464

This Mouse Monoclonal antibody specifically detects CD1a in FACS. It exhibits reactivity toward Human.

Quick Overview for CD1a antibody (APC) (ABIN7200464)

Target: CD1a

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD1a antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: OKT6

Product Details anti-CD1a Antibody (APC)

Purpose: CD1a APC Antibody

Characteristics: The clone OKT6, a mouse monoclonal antibody selectively recognizes 49- kDa type I transmembrane glycoprotein non-covalently associated with β2-microglobulin known as CD1a. The CD1a glycoprotein has structural similarities to MHC class I molecule and plays important role in antigen-presenting mechanism to T-cell receptors present on NK T-cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation NK T-cells, CD1a has been implicated in thymic T cell development. CD1a has been used as a marker for DCs in a range of human tumors and the density of CD1a DC has been associated with clinical outcome in patients with lung, colon, gastric, nasopharyngeal, laryngeal and tongue carcinomas.

Purification: Purified

Purity: >95 %

Immunogen: Human acute lymphoblastic leukemia cells

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for CD1a

Target: CD1a

Alternative Name: CD1a

Gene ID: 909

UniProt: P06126

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process