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CD14 antibody (AA 25-148) (FITC)

GMP Grade CD14 Reactivity: Human FACS Host: Mouse Monoclonal C-2386 FITC

Catalog No. ABIN7200491

Datasheet as PDF

Target See all CD14 Antibodies

CD14
Binding Specificity
8

6

5

5

4

4

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 25-148
Reactivity
229

43

36

24

23

22

22

21

17

16

15

14

13

13

12

9

7

7

6

4

4

2

1

1
Human
Host
196

59

16

3

2

1
Mouse
Compatible Secondaries
Clonality
217

59

1
Monoclonal
Conjugate
128

29

21

18

12

5

4

4

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD14 antibody is conjugated to FITC
Application
202

92

69

57

47

46

19

14

13

13

7

4

4

3

3

3

2

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Purpose

CD14 FITC Antibody

Characteristics

The clone C-2386, a mouse monoclonal antibody reacts with a human 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain cell surface antigen known as CD14. The CD14 expression is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. C-2386 binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes.

Purification

Purified

Purity

>95 %

Grade

GMP Grade

Immunogen

Recombinant fragment of human CD14 protein (around aa 25-148)

Clone

C-2386

Isotype

IgG1, kappa

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CD14 Reactivity: Human, Non-Human Primate FACS, WB, ELISA, IP Host: Mouse Monoclonal MEM-18 unconjugated

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CD14 Reactivity: Human, Mouse, Rat, Sheep, Dog, Rabbit WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C

Storage Comment

2-8°C, Conjugated antibodies should never be frozen.
Target

CD14

Alternative Name

CD14 (CD14 Products)

Gene ID

929

UniProt

P08571

Pathways

TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades