Recombinant EGFR (Panitumumab Biosimilar) antibody
Quick Overview for Recombinant EGFR (Panitumumab Biosimilar) antibody (ABIN7200662)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
Grade
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Purpose
- Panitumumab Biosimilar, Human EGFR/ErbB-1/HER1 Monoclonal Antibody
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Specificity
- The monoclonal antibody panitumumab biosimilar specifically binds to the human EGFR, ErbB-1 and HER1.
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Characteristics
- Panitumumab, a fully anti-EGFR (epidermal growth factor receptor, EGF receptor, ErbB-1 and HER1 in humans) human monoclonal antibody, is used for the treatment of refractory EGFR-expressing metastatic colorectal cancer in patients with non-mutated (wild-type) KRAS".
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Purification
- Protein A or G affinity column
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Purity
- >95 % by reducing SDS-PAGE
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- < 1 EU per 1 mg of the protein by the LAL method
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Immunogen
- The monoclonal antibody panitumumab biosimilar was produced in the Panitumumab biosimilar CHO stable cell line.
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Isotype
- IgG2
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Application Notes
- ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by panitumumab.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Buffer
- PBS, pH 7.4, no stabilizers or preservatives.
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Preservative
- Without preservative
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Storage
- 4°C,-20 °C
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Storage Comment
- 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
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Expiry Date
- 12 months
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- EGFR (Panitumumab Biosimilar)
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Alternative Name
- Panitumumab Biosimilar
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Target Type
- Biosimilar
Target
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