HTR3D antibody (AA 10-90)

Catalog No. ABIN7220252

The Rabbit Polyclonal anti-HTR3D antibody (ABIN7220252) specifically detects HTR3D in ELISA, WB and IF. The antibody is reactive with Human samples.

Quick Overview for HTR3D antibody (AA 10-90) (ABIN7220252)

Target: HTR3D (5-Hydroxytryptamine (serotonin) Receptor 3 Family Member D (HTR3D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR3D antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-HTR3D Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-SR-3D Polyclonal Antibody

Specificity: SR-3D Polyclonal Antibody detects endogenous levels of SR-3D protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human SR-3D at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HTR3D

Target: HTR3D (5-Hydroxytryptamine (serotonin) Receptor 3 Family Member D (HTR3D))

Alternative Name: SR-3D

Background: HTR3D, 5-hydroxytryptamine receptor 3D, 5-HT3-D, 5-HT3D, Serotonin receptor 3DThe 5-hydroxytryptamine receptor 3D encoded HTR3D belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 50kD

Gene ID: 200909

UniProt: Q70Z44