NT5C3 antibody (AA 30-110)

Catalog No. ABIN7222990

This Rabbit Polyclonal antibody specifically detects NT5C3 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for NT5C3 antibody (AA 30-110) (ABIN7222990)

Target: NT5C3 (5'-Nucleotidase, Cytosolic III (NT5C3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NT5C3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-NT5C3 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-NT5C3 Polyclonal Antibody

Specificity: NT5C3 Polyclonal Antibody detects endogenous levels of NT5C3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human NT5C3 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NT5C3

Target: NT5C3 (5'-Nucleotidase, Cytosolic III (NT5C3))

Alternative Name: NT5C3

Background: NT5C3, P5N1, UMPH1, HSPC233, Cytosolic 5'-nucleotidase 3, Cytosolic 5'-nucleotidase III, cN-III, Pyrimidine 5'-nucleotidase 1, P5'N-1, P5N-1, PN-I, Uridine 5'-monophosphate hydrolase 1, p36NT5C3A (5'-nucleotidase, cytosolic IIIA) encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in NT5C3A are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4.

Molecular Weight: 38kD

Gene ID: 51251

UniProt: Q9H0P0