AKAP4 antibody (AA 430-510)

Catalog No. ABIN7227254

The Rabbit Polyclonal anti-AKAP4 antibody (ABIN7227254) specifically detects AKAP4 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for AKAP4 antibody (AA 430-510) (ABIN7227254)

Target: AKAP4 (A Kinase (PRKA) Anchor Protein 4 (AKAP4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AKAP4 Antibody

Binding Specificity: AA 430-510

Purpose: Rabbit Anti-AKAP4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of AKAP4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human AKAP4 protein at AA range: 430-510

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AKAP4

Target: AKAP4 (A Kinase (PRKA) Anchor Protein 4 (AKAP4))

Alternative Name: AKAP4

Background: A-kinase anchor protein 4, AKAP-4, A-kinase anchor protein 82 kDa, AKAP 82, hAKAP82, Major sperm fibrous sheath protein, HI, Protein kinase A-anchoring protein 4, PRKA4The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP4 encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms. AKAP4 (A-Kinase Anchoring Protein 4) is a Protein Coding gene. Diseases associated with AKAP4 include Retinitis Pigmentosa 70. Among its related pathways are Activation of cAMP-Dependent PKA and DAG and IP3 signaling.

Molecular Weight: 93kD

Gene ID: 8852

UniProt: Q5JQC9