AKAP6 antibody (AA 30-110)

Catalog No. ABIN7227256

The Rabbit Polyclonal anti-AKAP6 antibody is suitable to detect AKAP6 in samples from Human and Rat. It has been validated for IHC and IF.

Quick Overview for AKAP6 antibody (AA 30-110) (ABIN7227256)

Target: AKAP6 (Akap6) (A Kinase (PRKA) Anchor Protein 6 (Akap6))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP6 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-AKAP6 Antibody

Binding Specificity: AA 30-110

Purpose: Rabbit Anti-AKAP6 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of AKAP6 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human AKAP6 protein at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AKAP6

Target: AKAP6 (Akap6) (A Kinase (PRKA) Anchor Protein 6 (Akap6))

Alternative Name: AKAP6

Background: A-kinase anchor protein 6, AKAP-6, A-kinase anchor protein 100 kDa, AKAP 100, Protein kinase A-anchoring protein 6, PRKA6, mAKAPAKAP6 (A-Kinase Anchoring Protein 6) is a Protein Coding gene. Among its related pathways are Activation of cAMP-Dependent PKA and DAG and IP3 signaling. The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP6 encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum.

Molecular Weight: 255kD

Gene ID: 9472

UniProt: Q13023

Pathways: cAMP Metabolic Process, Regulation of Muscle Cell Differentiation