ADCK2 antibody (AA 210-290)

Catalog No. ABIN7225816

The Rabbit Polyclonal anti-ADCK2 antibody (ABIN7225816) specifically detects ADCK2 in WB, ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for ADCK2 antibody (AA 210-290) (ABIN7225816)

Target: ADCK2 (AarF Domain Containing Kinase 2 (ADCK2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ADCK2 Antibody

Binding Specificity: AA 210-290

Purpose: Rabbit Anti-ADCK2 Polyclonal Antibody

Specificity: ADCK2 Polyclonal Antibody detects endogenous levels of ADCK2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ADCK2 at AA range: 210-290

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADCK2

Target: ADCK2 (AarF Domain Containing Kinase 2 (ADCK2))

Alternative Name: ADCK2

Background: ADCK2, AARF, Uncharacterized aarF domain-containing protein kinase 2ADCK2 (aarF domain containing kinase 2), also known as AARF, is a 626 amino acid single-pass membrane protein belonging to the protein kinase superfamily and the ADCK protein kinase family. The ADCK family consists of five paralogs in human (ADCK1-5). Encoded by a gene that maps to human chromosome 7q34, ADCK2 contains one protein kinase domain. ADCK2 participates in ATP and nucleotide binding, transferase functions and protein serine/threonine kinase activities. Expression of ADCK2 inversely correlates with cellular viability, suggesting elevated expression of ADCK2 may be essential for tumour survival. ADCK2 is necessary for cell proliferation of glioblastoma multiforme (GBM), a fatal primary brain tumor containing countless genetic and epigenetic alterations.

Molecular Weight: 69kD

Gene ID: 90956

UniProt: Q7Z695