CHRNA1 antibody (Internal Region)

Catalog No. ABIN7218616

The Rabbit Polyclonal anti-CHRNA1 antibody is suitable to detect CHRNA1 in samples from Human, Mouse and Rat. It has been validated for ELISA, WB and IF.

Quick Overview for CHRNA1 antibody (Internal Region) (ABIN7218616)

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CHRNA1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-AChRα1 Polyclonal Antibody

Specificity: AChRα1 Polyclonal Antibody detects endogenous levels of AChRα1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human AChRalpha1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,IF 1:100-300,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CHRNA1

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Alternative Name: AChRalpha1

Background: CHRNA1, ACHRA, CHNRA, Acetylcholine receptor subunit alphaThe muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 55kD

Gene ID: 1134

UniProt: P02708

Pathways: Skeletal Muscle Fiber Development