CHRNA1 antibody (Internal Region)

Catalog No. ABIN7219320

The Rabbit Polyclonal anti-CHRNA1 antibody (ABIN7219320) specifically detects CHRNA1 in ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CHRNA1 antibody (Internal Region) (ABIN7219320)

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CHRNA1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-AChRα1 Polyclonal Antibody

Specificity: AChRα1 Polyclonal Antibody detects endogenous levels of AChRα1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human AChRalpha1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CHRNA1

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Alternative Name: AChRalpha1

Background: CHRNA1, ACHRA, CHNRA, Acetylcholine receptor subunit alphaThe muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. CHRNA1 encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene ID: 1134

UniProt: P02708

Pathways: Skeletal Muscle Fiber Development