ASCL2 antibody (AA 1-80)

Catalog No. ABIN7222498

The Rabbit Polyclonal anti-ASCL2 antibody is suitable to detect ASCL2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for ASCL2 antibody (AA 1-80) (ABIN7222498)

Target: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASCL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ASCL2 Antibody

Binding Specificity: AA 1-80

Purpose: Rabbit Anti-Mash2 Polyclonal Antibody

Specificity: Mash2 Polyclonal Antibody detects endogenous levels of Mash2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Mash2 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ASCL2

Target: ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))

Alternative Name: Mash2

Background: ASCL2, BHLHA45, HASH2, Achaete-scute homolog 2, ASH-2, hASH2, Class A basic helix-loop-helix protein 45, bHLHa45, Mash2ASCL2 is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.

Molecular Weight: 25kD

Gene ID: 430

UniProt: Q99929

Pathways: Stem Cell Maintenance