CHRNB1 antibody (AA 10-90)

Catalog No. ABIN7219326

The Rabbit Polyclonal anti-CHRNB1 antibody is suitable to detect CHRNB1 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for CHRNB1 antibody (AA 10-90) (ABIN7219326)

Target: CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CHRNB1 Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-AChRβ1 Polyclonal Antibody

Specificity: AChRβ1 Polyclonal Antibody detects endogenous levels of AChRβ1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human AChRbeta1 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:5000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CHRNB1

Target: CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

Alternative Name: AChRbeta1

Background: CHRNB1, ACHRB, CHRNB, Acetylcholine receptor subunit betaThe muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. CHRNB encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

Molecular Weight: 55kD

Gene ID: 1140

UniProt: P11230

Pathways: Synaptic Membrane