ADAM15 antibody (AA 50-130)

Catalog No. ABIN7227212

This Rabbit Polyclonal antibody specifically detects ADAM15 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ADAM15 antibody (AA 50-130) (ABIN7227212)

Target: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADAM15 Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-ADA15 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ADA15 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ADA15 protein at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADAM15

Target: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Alternative Name: ADA15

Background: Metalloprotease RGD disintegrin protein, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15, MDC-15, MetargidinThe protein encoded by ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Molecular Weight: 94kD

Gene ID: 8751

UniProt: Q13444