ADAR antibody (AA 1140-1220)

Catalog No. ABIN7218958

The Rabbit Polyclonal anti-ADAR antibody is suitable to detect ADAR in samples from Human, Mouse and Rat. It has been validated for ELISA and IHC (p).

Quick Overview for ADAR antibody (AA 1140-1220) (ABIN7218958)

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAR antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ADAR Antibody

Binding Specificity: AA 1140-1220

Purpose: ADAR1 Polyclonal Antibody

Specificity: ADAR1 Polyclonal Antibody detects endogenous levels of ADAR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human ADAR1 at AA range: 1140-1220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ADAR

Target: ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Alternative Name: ADAR1

Background: Rabbit Anti-ADAR1 Polyclonal Antibody,ADAR, ADAR1, DSRAD, G1P1, IFI4, Double-stranded RNA-specific adenosine deaminase, DRADA, 136 kDa double-stranded RNA-binding protein, p136, Interferon-inducible protein 4, IFI-4, K88DSRBP,ADAR encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.,Double-stranded RNA-specific adenosine deaminase

Gene ID: 103

UniProt: P55265

Pathways: Protein targeting to Nucleus