ADK antibody (AA 1-80)

Catalog No. ABIN7219566

This Rabbit Polyclonal antibody specifically detects ADK in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ADK antibody (AA 1-80) (ABIN7219566)

Target: ADK (Adenosine Kinase (ADK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ADK Antibody

Binding Specificity: AA 1-80

Purpose: Rabbit Anti-ADK Polyclonal Antibody

Specificity: ADK Polyclonal Antibody detects endogenous levels of ADK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human ADK at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADK

Target: ADK (Adenosine Kinase (ADK))

Alternative Name: ADK

Background: ADK, Adenosine kinase, AK, Adenosine 5'-phosphotransferaseADK an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 40kD

Gene ID: 132

UniProt: P55263

Pathways: Ribonucleoside Biosynthetic Process