ADCY2 antibody (AA 490-570)

Catalog No. ABIN7227218

The Rabbit Polyclonal anti-ADCY2 antibody (ABIN7227218) specifically detects ADCY2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ADCY2 antibody (AA 490-570) (ABIN7227218)

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADCY2 Antibody

Binding Specificity: AA 490-570

Purpose: Rabbit Anti-ADCY2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ADCY2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ADCY2 protein at AA range: 490-570

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADCY2

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Alternative Name: ADCY2

Background: Adenylate cyclase type 2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2ADCY2 (Adenylate Cyclase 2) is a Protein Coding gene. Among its related pathways are GABAergic synapse and Calcium signaling pathway. ADCY2 encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.

Molecular Weight: 120kD

Gene ID: 108

UniProt: Q08462

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma