ADCY4 antibody (AA 170-250)

Catalog No. ABIN7220176

The Rabbit Polyclonal anti-ADCY4 antibody is suitable to detect ADCY4 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for ADCY4 antibody (AA 170-250) (ABIN7220176)

Target: ADCY4 (Adenylate Cyclase 4 (ADCY4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ADCY4 Antibody

Binding Specificity: AA 170-250

Purpose: Rabbit Anti-A Cyclase IV Polyclonal Antibody

Specificity: A Cyclase IV Polyclonal Antibody detects endogenous levels of A Cyclase IV protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human A Cyclase IV at AA range: 170-250

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADCY4

Target: ADCY4 (Adenylate Cyclase 4 (ADCY4))

Alternative Name: A Cyclase IV

Background: ADCY4, Adenylate cyclase type 4, ATP pyrophosphate-lyase 4, Adenylate cyclase type IV, Adenylyl cyclase 4ADCY4 encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants.

Molecular Weight: 120kD

Gene ID: 196883

UniProt: Q8NFM4

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma