ART4 antibody (pTyr362)

Catalog No. ABIN7212936

The Rabbit Polyclonal anti-ART4 antibody is suitable to detect ART4 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IF.

Quick Overview for ART4 antibody (pTyr362) (ABIN7212936)

Target: ART4 (ADP-Ribosyltransferase 4 (Dombrock Blood Group) (ART4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ART4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-ART4 Antibody

Binding Specificity: pTyr362

Purpose: Rabbit Anti-Dok-1 (phospho Tyr362) Polyclonal Antibody

Specificity: Phospho-Dok-1 (Y362) Polyclonal Antibody detects endogenous levels of Dok-1 protein only when phosphorylated at Y362.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Dok-1 Phospho-Tyr362

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ART4

Target: ART4 (ADP-Ribosyltransferase 4 (Dombrock Blood Group) (ART4))

Alternative Name: Dok-1

Background: DOK1, Docking protein 1, Downstream of tyrosine kinase 1, p62(dok), pp62Docking protein 1 encoded by DOK1 is part of a signal transduction pathway downstream of receptor tyrosine kinases. Docking protein 1 is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Several transcript variants encoding different isoforms have been found for DOK1.

Molecular Weight: 55kD

Gene ID: 1796

UniProt: Q99704