ART4 antibody (pTyr398)

Catalog No. ABIN7220072

The Rabbit Polyclonal anti-ART4 antibody (ABIN7220072) specifically detects ART4 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ART4 antibody (pTyr398) (ABIN7220072)

Target: ART4 (ADP-Ribosyltransferase 4 (Dombrock Blood Group) (ART4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ART4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ART4 Antibody

Binding Specificity: pTyr398

Purpose: Rabbit Anti-Dok-1 (phospho Tyr398) Polyclonal Antibody

Specificity: Phospho-Dok-1 (Y398) Polyclonal Antibody detects endogenous levels of Dok-1 protein only when phosphorylated at Y398.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Dok-1 Phospho-Tyr398

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ART4

Target: ART4 (ADP-Ribosyltransferase 4 (Dombrock Blood Group) (ART4))

Alternative Name: Dok-1

Background: DOK1, Docking protein 1, Downstream of tyrosine kinase 1, p62(dok), pp62Docking protein 1 encoded by DOK1 is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Several transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 62kD

Gene ID: 1796

UniProt: Q99704