alpha 1 Adrenergic Receptor antibody (AA 110-190)
Quick Overview for alpha 1 Adrenergic Receptor antibody (AA 110-190) (ABIN7219796)
Target
See all alpha 1 Adrenergic Receptor (ADRA1A) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 110-190
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Purpose
- AR-α1A Polyclonal Antibody
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Specificity
- AR-α1A Polyclonal Antibody detects endogenous levels of AR-α1A protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human AR-alpha1A at AA range: 110-190
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))
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Alternative Name
- AR-alpha1A
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Background
- Rabbit Anti-AR-α1A Polyclonal Antibody,ADRA1A, ADRA1C, Alpha-1A adrenergic receptor, Alpha-1A adrenoreceptor, Alpha-1A adrenoceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c,Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. ADRA1A encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.,Alpha-1A adrenergic receptor
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Gene ID
- 148
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UniProt
- P35348
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Pathways
- AMPK Signaling
Target
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