ALDH1A2 antibody (AA 390-470)
Quick Overview for ALDH1A2 antibody (AA 390-470) (ABIN7225686)
Target
See all ALDH1A2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 390-470
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Purpose
- ALDH1A2 Polyclonal Antibody
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Specificity
- ALDH1A2 Polyclonal Antibody detects endogenous levels of ALDH1A2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human ALDH1A2 at AA range: 390-470
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))
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Alternative Name
- ALDH1A2
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Background
- Rabbit Anti-ALDH1A2 Polyclonal Antibody,ALDH1A2, RALDH2, Retinal dehydrogenase 2, RALDH 2, RalDH2, Aldehyde dehydrogenase family 1 member A2, Retinaldehyde-specific dehydrogenase type 2, RALDH(II),This protein ALDH1A2 belongs to the aldehyde dehydrogenase family of proteins. The product of ALDH1A2 (aldehyde dehydrogenase 1 family member A2) is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for ALDH1A2.,Retinal dehydrogenase 2
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Gene ID
- 8854
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UniProt
- O94788
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Pathways
- Retinoic Acid Receptor Signaling Pathway
Target
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