AL1A3 antibody (AA 290-370)

Catalog No. ABIN7227264

The Rabbit Polyclonal anti-AL1A3 antibody is suitable to detect AL1A3 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for AL1A3 antibody (AA 290-370) (ABIN7227264)

Target: AL1A3 (LOC101450893) (Aldehyde Dehydrogenase X, Mitochondrial (LOC101450893))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AL1A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AL1A3 Antibody

Binding Specificity: AA 290-370

Purpose: Rabbit Anti-AL1A3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of AL1A3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human AL1A3 protein at AA range: 290-370

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AL1A3

Target: AL1A3 (LOC101450893) (Aldehyde Dehydrogenase X, Mitochondrial (LOC101450893))

Alternative Name: AL1A3

Background: Aldehyde dehydrogenase family 1 member A3, Aldehyde dehydrogenase 6, Retinaldehyde dehydrogenase 3, RALDH-3, RalDH3ALDH1A3 (Aldehyde Dehydrogenase 1 Family Member A3) is a Protein Coding gene. Diseases associated with ALDH1A3 include Microphthalmia, Isolated 8 and Isolated Microphthalmia. Among its related pathways are Histidine metabolism and Drug metabolism - cytochrome P450. ALDH1A3 encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in ALDH1A3 have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.

Molecular Weight: 56kD

Gene ID: 220

UniProt: P47895