ALKB2 antibody (AA 140-220)

Catalog No. ABIN7227266

This Rabbit Polyclonal antibody specifically detects ALKB2 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for ALKB2 antibody (AA 140-220) (ABIN7227266)

Target: ALKB2 (AlkB2 Gene Product (ALKB2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALKB2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-ALKB2 Antibody

Binding Specificity: AA 140-220

Purpose: Rabbit Anti-ALKB2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ALKB2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ALKB2 protein at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ALKB2

Target: ALKB2 (AlkB2 Gene Product (ALKB2))

Alternative Name: ALKB2

Background: DNA oxidative demethylase ALKBH2, Alkylated DNA repair protein alkB homolog 2, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, Oxy DC1ALKBH2 (AlkB Homolog 2, Alpha-Ketoglutarate Dependent Dioxygenase) is a Protein Coding gene. Among its related pathways are DNA Damage Reversal and DNA Double-Strand Break Repair. The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E.coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine.

Molecular Weight: 28kD

Gene ID: 121642

UniProt: Q6NS38