APBA1 antibody (AA 180-260)

Catalog No. ABIN7227322

This Rabbit Polyclonal antibody specifically detects APBA1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for APBA1 antibody (AA 180-260) (ABIN7227322)

Target: APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APBA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-APBA1 Antibody

Binding Specificity: AA 180-260

Purpose: APBA1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of APBA1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human APBA1 protein at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for APBA1

Target: APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))

Alternative Name: APBA1

Background: Rabbit Anti-APBA1 Polyclonal Antibody,Amyloid-beta A4 precursor protein-binding family A member 1, Adapter protein X11alpha, Neuron-specific X11 protein, Neuronal Munc18-1-interacting protein 1, Mint-1,APBA1 (Amyloid Beta Precursor Protein Binding Family A Member 1) is a Protein Coding gene. Diseases associated with APBA1 include Alzheimer Disease and Neuronal Intranuclear Inclusion Disease. Among its related pathways are Protein-protein interactions at synapses and Neurotransmitter Release Cycle. The protein encoded by APBA1 is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.,APBA1

Gene ID: 320

UniProt: Q02410

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport