ANAPC4 antibody

Catalog No. ABIN7227326

This Rabbit Polyclonal antibody specifically detects ANAPC4 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for ANAPC4 antibody (ABIN7227326)

Target: ANAPC4 (Anaphase Promoting Complex Subunit 4 (ANAPC4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ANAPC4 Antibody

Purpose: Rabbit Anti-APC4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of APC4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human APC4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ANAPC4

Target: ANAPC4 (Anaphase Promoting Complex Subunit 4 (ANAPC4))

Alternative Name: APC4

Background: Anaphase-promoting complex subunit 4(APC4), Cyclosome subunit 4A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene. APC4 (Anaphase Promoting Complex Subunit 4) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Cell Cycle, Mitotic.

Molecular Weight: 88kD

Gene ID: 29945

UniProt: Q9UJX5

Pathways: M Phase