Angiomotin antibody (AA 710-790)

Catalog No. ABIN7227280

The Rabbit Polyclonal anti-Angiomotin antibody (ABIN7227280) specifically detects Angiomotin in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for Angiomotin antibody (AA 710-790) (ABIN7227280)

Target: Angiomotin (AMOT)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiomotin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Angiomotin Antibody

Binding Specificity: AA 710-790

Purpose: Rabbit Anti-AMOT Polyclonal Antibody

Specificity: The antibody detects endogenous levels of AMOT protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human AMOT protein at AA range: 710-790

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Angiomotin

Target: Angiomotin (AMOT)

Alternative Name: AMOT

Background: AngiomotinAMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 119kD

Gene ID: 154796

UniProt: Q4VCS5

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size