APOBEC3D/F (AA 210-290) antibody

Catalog No. ABIN7213630

This Rabbit Polyclonal antibody specifically detects APOBEC3D/F in IHC, ELISA, WB and IF. It exhibits reactivity toward Human and Monkey.

Quick Overview for APOBEC3D/F (AA 210-290) antibody (ABIN7213630)

Target: APOBEC3D/F

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details

Binding Specificity: AA 210-290

Purpose: Rabbit Anti-APOBEC3D/F Polyclonal Antibody

Specificity: APOBEC3D/F Polyclonal Antibody detects endogenous levels of APOBEC3D/F protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human APOBEC3D/F at AA range: 210-290

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: APOBEC3D/F

Background: APOBEC3D, Probable DNA dC->dU-editing enzyme APOBEC-3D, APOBEC3F, DNA dC->dU-editing enzyme APOBEC-3F, Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3FAPOBEC3F is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 40kD

Gene ID: 200316, 140564

UniProt: Q96AK3, Q8IUX4