AATK antibody (AA 1110-1190)
Quick Overview for AATK antibody (AA 1110-1190) (ABIN7229418)
Target
See all AATK AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1110-1190
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Purpose
- LMTK1 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of LMTK1 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human LMTK1 protein at AA range: 1110-1190
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- AATK (Apoptosis-Associated tyrosine Kinase (AATK))
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Alternative Name
- LMTK1
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Background
- Rabbit Anti-LMTK1 Polyclonal Antibody,Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BP,The protein encoded by AATK contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. AATK is induced during apoptosis, and expression of AATK may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. AATK has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for AATK.,LMTK1
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Molecular Weight
- observerd band 151kDa
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Gene ID
- 9625
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UniProt
- Q6ZMQ8
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Pathways
- RTK Signaling, Regulation of Cell Size
Target
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