Aprataxin antibody (AA 11-60)

Catalog No. ABIN7227342

This Rabbit Polyclonal antibody specifically detects Aprataxin in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Aprataxin antibody (AA 11-60) (ABIN7227342)

Target: Aprataxin (APTX)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aprataxin antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Aprataxin Antibody

Binding Specificity: AA 11-60

Purpose: APTX Polyclonal Antibody

Specificity: The antibody detects endogenous levels of APTX protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human APTX protein at AA range: 11-60

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Aprataxin

Target: Aprataxin (APTX)

Alternative Name: APTX

Background: Rabbit Anti-APTX Polyclonal Antibody,Aprataxin, Forkhead-associated domain histidine triad-like protein, FHA-HIT,APTX encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in APTX have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for APTX.,APTX

Gene ID: 54840

UniProt: Q7Z2E3

Pathways: DNA Damage Repair, Chromatin Binding