Aquaporin 4 antibody

Catalog No. ABIN7201263

The Mouse Monoclonal anti-Aquaporin 4 antibody has been validated for WB, IF and IHC (p). It is suitable to detect Aquaporin 4 in samples from Human, Mouse and Rat.

Quick Overview for Aquaporin 4 antibody (ABIN7201263)

Target: Aquaporin 4 (AQP4)

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Aquaporin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Aquaporin 4 Antibody

Purpose: Aquaporin 4 Monoclonal Antibody

Specificity: The antibody detects endogenous Aquaporin 4 proteins.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

Immunogen: Synthetic Peptide

Isotype: IgG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000), IF (1:100-1:200), IHC-P (1:50-1:300).

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Aquaporin 4

Target: Aquaporin 4 (AQP4)

Alternative Name: Aquaporin 4

Background: Mouse Anti-Aquaporin 4 Monoclonal Antibody,AQP4, Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4,AQP4 encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. Aquaporin 4 is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for AQP4. A recent study provided evidence for translational readthrough in AQP4 and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.,Aquaporin-4

Gene ID: 361

UniProt: P55087

Pathways: Sensory Perception of Sound