Arc antibody (AA 70-150)

Catalog No. ABIN7227356

The Rabbit Polyclonal anti-Arc antibody is suitable to detect Arc in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for Arc antibody (AA 70-150) (ABIN7227356)

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Arc antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Arc Antibody

Binding Specificity: AA 70-150

Purpose: Rabbit Anti-ARC Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ARC protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ARC protein at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Arc

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Alternative Name: ARC

Background: ARC/ARG3.1, Activity-regulated gene 3.1 protein homolog, Arg3.1Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.

Molecular Weight: 43kD

Gene ID: 23237

UniProt: Q7LC44