AVPR1A antibody (AA 11-60)

Catalog No. ABIN7227434

The Rabbit Polyclonal anti-AVPR1A antibody (ABIN7227434) specifically detects AVPR1A in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for AVPR1A antibody (AA 11-60) (ABIN7227434)

Target: AVPR1A (Arginine Vasopressin Receptor 1A (AVPR1A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AVPR1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-AVPR1A Antibody

Binding Specificity: AA 11-60

Purpose: Rabbit Anti-AVPR1A Polyclonal Antibody

Specificity: The antibody detects endogenous levels of AVPR1A

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human AVPR1A protein at AA range: 11-60

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AVPR1A

Target: AVPR1A (Arginine Vasopressin Receptor 1A (AVPR1A))

Alternative Name: AVPR1A

Background: Vasopressin V1a receptor, V1aR, AVPR V1a, Antidiuretic hormone receptor 1a, Vascular/hepatic-type arginine vasopressin receptorThe protein encoded by AVPR1A acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.

Molecular Weight: 55kD

Gene ID: 552

UniProt: P37288

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Response to Water Deprivation, Regulation of Carbohydrate Metabolic Process