ARRDC2 antibody (AA 110-190)

Catalog No. ABIN7213688

The Rabbit Polyclonal anti-ARRDC2 antibody is suitable to detect ARRDC2 in samples from Human and Mouse. It has been validated for IHC, ELISA, WB and IF.

Quick Overview for ARRDC2 antibody (AA 110-190) (ABIN7213688)

Target: ARRDC2 (Arrestin Domain Containing 2 (ARRDC2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARRDC2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ARRDC2 Antibody

Binding Specificity: AA 110-190

Purpose: Rabbit Anti-ARRDC2 Polyclonal Antibody

Specificity: ARRDC2 Polyclonal Antibody detects endogenous levels of ARRDC2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ARRDC2 at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ARRDC2

Target: ARRDC2 (Arrestin Domain Containing 2 (ARRDC2))

Alternative Name: ARRDC2

Background: ARRDC2, PP2703, Arrestin domain-containing protein 2ARRDC1, ARRDC2 (which exists as multiple alternatively spliced isoforms), ARRDC4 and ARRDC5 are arrestin domain-containing proteins that are encoded by genes which map to human chromosomes 9, 15 and 19. Chromosome 9, on which the ARRDC1 gene is localized, contains 145 million base pairs and comprises 4 % of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. The ARRDC2 and ARRDC5 genes map to chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. Unlike other ARRDC genes, the ARRDC4 gene maps to human chromosome 15, which houses over 700 genes and comprises nearly 3 % of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

Molecular Weight: 44kD

Gene ID: 27106

UniProt: Q8TBH0