Autoimmune Myocardial Disease antibody (AA 380-460)

Catalog No. ABIN7227276

This Rabbit Polyclonal antibody specifically detects Autoimmune Myocardial Disease in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Autoimmune Myocardial Disease antibody (AA 380-460) (ABIN7227276)

Target: Autoimmune Myocardial Disease (AMD)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Autoimmune Myocardial Disease antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Autoimmune Myocardial Disease Antibody

Binding Specificity: AA 380-460

Purpose: Rabbit Anti-AMD Polyclonal Antibody

Specificity: The antibody detects endogenous levels of AMD protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human AMD protein at AA range: 380-460

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Autoimmune Myocardial Disease

Target: Autoimmune Myocardial Disease (AMD)

Alternative Name: AMD

Background: Peptidylamidoglycolate lyase, PALPAM encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Molecular Weight: 107kD

Gene ID: 5066

UniProt: P19021