BTLA antibody (Internal Region)

Catalog No. ABIN7219860

This Rabbit Polyclonal antibody specifically detects BTLA in WB, FACS, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for BTLA antibody (Internal Region) (ABIN7219860)

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTLA antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BTLA Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-CD272 Polyclonal Antibody

Specificity: CD272 Polyclonal Antibody detects endogenous levels of CD272 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CD272

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:200-1:1000,Flow Cyt 1:200-1:400,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BTLA

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Alternative Name: CD272

Background: BTLA, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein, CD antigen CD272BTLA encodes a member of the immunoglobulin superfamily. B and T lymphocyte associated contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.

Molecular Weight: 36kD

Gene ID: 151888

UniProt: Q7Z6A9

Pathways: Cancer Immune Checkpoints