BCAP31 antibody (AA 120-200)

Catalog No. ABIN7213764

This Rabbit Polyclonal antibody specifically detects BCAP31 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for BCAP31 antibody (AA 120-200) (ABIN7213764)

Target: BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAP31 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BCAP31 Antibody

Binding Specificity: AA 120-200

Purpose: Rabbit Anti-BAP31 Polyclonal Antibody

Specificity: BAP31 Polyclonal Antibody detects endogenous levels of BAP31 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human BAP31 at AA range: 120-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BCAP31

Target: BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Alternative Name: BAP31

Background: BCAP31, BAP31, DXS1357E, B-cell receptor-associated protein 31, BCR-associated protein 31, Bap31, 6C6-AG tumor-associated antigen, Protein CDM, p28BCAP31 encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein (B-cell receptor-associated protein 31) is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of BCAP31 results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16.

Molecular Weight: 28kD

Gene ID: 10134

UniProt: P51572

Pathways: Positive Regulation of Endopeptidase Activity