BAG1 antibody (Internal Region)

Catalog No. ABIN7218252

This Rabbit Polyclonal antibody specifically detects BAG1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for BAG1 antibody (Internal Region) (ABIN7218252)

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BAG1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Bag-1 Polyclonal Antibody

Specificity: Bag-1 Polyclonal Antibody detects endogenous levels of Bag-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Bag-1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for BAG1

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Alternative Name: Bag-1

Background: BAG1, HAP, BAG family molecular chaperone regulator 1, BAG-1, Bcl-2-associated athanogene 1The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. BAG family molecular chaperone regulator 1 encoded by BAG1 binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.

Molecular Weight: 35kD

Gene ID: 573

UniProt: Q99933